Currently there are lots of discussions on the use of wireframing with tools such as Dreamweaver of Visio or Powerpoint. Some people argue that we should move away from wireframing altogether and start prototyping.
In Your Designs are Modular, but are your Artifacts? Nathan Curtis elaborates on ways to improve reuse in wireframing.
How I jump to my conclusions said
[...] Some time ago I blogged on wireframing or prototyping. [...]